In the study by Kremer et al. [59], the infection of C57BL/6 mice but not of C3H/HeJ mice with BCG induced the massive production of TNF-α in the serum and an increase in Fas and Fas ligand (FasL) expression in the T cells, resulting in a T-cell proliferation defect [59]. The gene discussed is FASLG; the disease is infection.