Single-walled carbon nanotubes (SWNTs) were coupled to the topoisomerase I inhibitor (SN38) and anti-EGFR antibody (cetuximab) for the delivery of SN38 to colon cancer cells by Lee et al. SWNT25/Py38 uptake was lower in the absence of the antibody than in the presence of the antibody, and the greatest uptake of SWNT25/Py38 was found in HCT-116 rather than HT29 or SW-620. Here, EGFR is linked to colonic neoplasm.