PGR and colonic neoplasm: In this regard, earlier studies reported low expression of PR in normal and malignant colonic tissues [67,68,69,70], as well as in human female (HT29, COLO-320, and SW48) and male (LoVo, SW620, Caco-2, T84, and SW1116) colon cancer cell lines (Table 1 and Table 2) [68,72].