In this study, we describe three additional cases of DDMN; the first reported case of donor-derived chronic myelomonocytic leukemia (CMML), one acute myeloid leukemia (AML) with t(8;21)(q22;22); <i>RUNX1-RUNX1T1</i> and one donor-derived MDS with deletion 5q. This evidence concerns the gene RUNX1 and acute myeloid leukemia.