To further validate the relationship between miR-138 and APT1 and their roles in atherosclerosis, we detected the expression of APT1 by the overexpression and inhibition of miR-138 expression and found that APT1 is inversely associated with miR-138 expression; overexpression of miR-138 can inhibit APT1, and vice versa (p < 0.05) (Figure 2D,E). Here, LYPLA1 is linked to atherosclerosis.