In terms of type 2 diabetes, Camino et al. described transforming growth factor-beta 1 (TGFBI), caveolae-associated protein 1 (CAVN1), monocyte differentiation antigen CD14 (CD14), mimecan, thrombospondin-1, fatty-acid-binding protein-4 (FABP-4) and neuroblast differentiation-associated protein AHNAK (AHNAK) contained in sEVs from morbid obese visceral (VAT) could be used as biomarkers [46]. The gene discussed is TGFB1; the disease is type 2 diabetes mellitus.