Several scoring systems have been developed to prognosticate survival in patients with brain metastases and thus aid clinicians in treatment decisions regarding WBRT: Radiation Therapy Oncology Group (RTOG) recursive partitioning analysis (RPA) [15], graded prognostic assessment (GPA) [16], and diagnosis-specific GPA (Lung-molGPA score) that includes assessment of EGFR and ALK alterations in non-small cell lung cancer (NSCLC) [11,17]. This evidence concerns the gene EGFR and non-small cell lung carcinoma.