To validate the array data, BPS of the respective genes of interest was performed, confirming that CYP2E1 was significantly hypomethylated in the PD cortex at the CpGs sites investigated (sum score: control 21.58 ± 8.78; PD 11.98 ± 5.3; p = 0.001; Figure 2A). The gene discussed is CYP2E1; the disease is Parkinson disease.