Multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), acute disseminated encephalomyelitis (ADEM), myelin oligodendrocyte glycoprotein (MOG) encephalomyelitis, and idiopathic transverse myelitis (TM) represent the main diseases characterized by autoimmune demyelination [1,2]. This evidence concerns the gene MOG and neuromyelitis optica.