In a study on triple-negative breast cancer (TNBC) treated with histone deacetylase (HDAC) inhibitors, Fang et al. [87] discovered that the induction of POX/PRODH played an anti-apoptotic role, while the lack of the enzyme significantly increased HDAC inhibitor-induced apoptosis. The gene discussed is HDAC9; the disease is triple-negative breast carcinoma.