Male BRCA2 carriers are more frequently affected by breast (OR, 5.47; 95% CI, 4.06–7.37; p < 0.001) and prostate (OR, 1.39; 95% CI, 1.09–1.78; p = 0.008) cancers and pancreatic cancers (OR, 3.00; 95% CI, 1.55–5.81; p = 0.001). The gene discussed is BRCA2; the disease is pancreatic neoplasm.