From the previous study of our group, the dysregulated proteins AMBP, KLK3, LMAN2, and TTR were found dysregulated in urine and tumor tissue from PCa patients, while SECTM1 was only found in urine from PCa patients, and CDH1 and EFEMP1 were only in PCa tissue. Here, KLK3 is linked to posterior cortical atrophy.