The analysis of the urine proteogenome profile of PCa patients revealed 6 differentially abundant mutant protein isoforms, namely AMBP*A286G, SLC9B1*N70S, HSPG2*Q1062H, ZNF624*S207F, VASN*R161Q, and CD55*S162L. This evidence concerns the gene HSPG2 and posterior cortical atrophy.