The native form of AMBP, CDH1, EFEMP1, HSPG2, ITIH4, KLK3, LMAN2, and PTGDS proteins was found dysregulated in urine from PCa patients, but only the mutant protein isoforms (AMBP*A286G; HSPG2*Q1062H) were found dysregulated (Figure S2). The gene discussed is EFEMP1; the disease is posterior cortical atrophy.