Neither the MassSpec nor the ExoRNA comparator models could effectively differentiate between the three cancer groups (Gs3 + 3, Gs3 + 4, Gs ≥ 4 + 3); however, ExoRNA was much better at separating PCa and No Cancer (NC) samples (AUC 0.84, Figure 1B,C). This evidence concerns the gene DNAJC21 and posterior cortical atrophy.