To test the effects of mitochondrial Kv1.3 inhibitors in multiple myeloma cells, we incubated the human multiple myeloma cell lines RPMI-8226 and L-363 with increasing concentrations of PAPTP and PCARBTP (range 0.05 to 10 μM) for 24 h (Figure 1b). Here, KCNA3 is linked to plasma cell myeloma.