The correlations between PD-L1 expression and TNM stage (I vs. II–III: OR = 0.45, 95% CI:0.34–0.60, p = 0.000), smoking status (Yes vs. No: OR = 1.43, 95% CI:1.14–1.80, p = 0.002), and lymph node metastases (N+ vs. N: OR = 1.97, 95% CI:1.26–3.08, p = 0.003) were examined. Here, CD274 is linked to metastatic malignant neoplasm in the lymph nodes.