PPARGC1A and cancer: Additionally, Pdk4 levels tended to increase in the SAT of cancer patients with respect to controls (mean 2.09 ± 1.00 vs. 1.46 ± 0.90) (p = 0.066) (Figure 1A), whereas no changes in Pgc1α expression were detected in cancer patients with respect to controls (median 1.40 IQR 0.80; 2.45 vs. 1.17 IQR 0.68; 1.42) (p = 0.179).