As shown in Figure 2A, Ucp1 expression levels were significantly decreased in cachectic (median 0.56 IQR 0.35; 1.39) and non-cachectic (median 0.61 IQR 0.26; 0.71) cancer patients compared to controls (median 1.17 IQR 0.85; 1.67) (p = 0.033 and p = 0.020, respectively). The gene discussed is UCP1; the disease is cancer.