In Western blot analysis performed in a subset of samples, we documented significantly higher UCP1 protein levels in pancreatic cancer patients when compared to colorectal cancer patients (median 1.00 IQR 0.73; 1.11 vs. 0.36 IQR 0.31;0.41) (p = 0.002) and to controls (median 0.37 IQR 0.30; 1.00) (p = 0.031) (Figure 3B). This evidence concerns the gene UCP1 and familial pancreatic carcinoma.