Arenaza et al., in a pharmacoeconomic multicenter Spanish study in de novo FLT3 positive AML patients from the RATIFY study, showed an overall cost of EUR 121,374 in non-alloHSCT patients and EUR 159,900 (no midostaurin arm) in alloHSCT patients. This evidence concerns the gene FLT3 and acute myeloid leukemia.