miR-34a is upregulated in neuroblastoma IMR-5 and SK-N-AS cells in response to CBN (Figure 2F), which may mechanically be through p53-dependent transactivation in IMR-5 and p53-independent-transactivation in SK-N-AS (Figure 2G,H) [38,42]. This evidence concerns the gene TP53 and neuroblastoma.