HIF1A and glioblastoma: According to this result, a deepened analysis of the molecular players, already described as participating in regulating the neuronal differentiation in GBM cells [9], revealed that a short-term HDI administration is sufficient to potently reduce, besides TCF4, the protein levels of HIF-1α, β-catenin, and TCF1 (Figure 3C and Supplementary Figure S3B–D).