IFNA1 and central nervous system cancer: Since previous studies demonstrated that inflammation and IFN signaling, besides regulating leukocyte recruitment and activation, play a pivotal role in sustaining the pro-migrating/invasive capability of cancer cells, including glioma [16], we hypothesized that this inhibition of IFN/inflammatory genes could contribute to the impairment of GBM cell motility exerted by TSA and SAHA.