Other DNA methylation markers linked to CRC include SFRP2 (obtainable from stool samples, with a sensitivity and specificity of 77%, [102]), VIM (obtainable from the serum, with a sensitivity of detection of 36.1%, 45.2%, 55.4%, and 85.7% for CRC stages 1 to 4, respectively, when used in combination with traditional CEA analysis, [103,104]), FBN2, and TCERG1 (sensitivities of 86% and 99%, respectively, if detected from tumor tissue) [105]. This evidence concerns the gene CEACAM5 and colorectal carcinoma.