RAC1 and gastric cancer: In addition, the expression of sLex antigen in gastric cancer cells induces an increased invasive phenotype through the activation of tyrosine-protein kinase Met, in association with proto-oncogene tyrosine-protein kinase Src, focal adhesion kinase (FAK), cell division control protein 42 homolog (Cdc42), ras-related C3 botulinum toxin substrate 1 (Rac1) and ras homologous protein (RhoA) GTPases activation [67].