While the incomplete synthesis is a phenomenon that occurs in the early stages of cancer progression and leads to the appearance of truncated forms of O-glycans (such as Tn or sTn antigens), the neosynthesis takes place in advanced stages of neoplasia and is associated with the induction of genes involved in carbohydrate synthesis, and derives in the formation of de novo antigens such as sLea or sLe-x [1,30,41,42,75]. Here, EEF1A2 is linked to cancer.