MGAT5 and central nervous system cancer: On the other hand, the increased expression of β1-6 branched N-oligosaccharides, catalysed by the golgi enzyme N-acetylglucosaminyl transferase-V (GnT-V), is also related to cancer progression and aggressiveness, particularly in the breast, colon, oesophagus gliomas and endometrium [12,13].