In addition, the inflammatory cascade might contribute to the development of an arrhythmogenic milieu by inducing complex alterations in atrial myocardiocytes [39].The prominent role of IL-6 in atrial fibrillation patients without COVID-19 has been recently linked to early neurological deterioration, defined as a ∆ ≥ 4 points in the National Institute of Health Stroke Scale (NIHSS) between admission and after 24 h. Here, IL6 is linked to atrial fibrillation.