With regard to both chronic and aggressive periodontitis, research focused on the polymorphisms of protein-coding genes involved in the inflammatory process and in the immune response, including histocompatibility antigens [9,10], IgG class antibodies [11] and their receptors [12,13,14], as well as CD14 molecules [15,16], toll-like receptors [17], vitamin D receptors [18] and other cellular receptors [19,20,21]. Here, CD14 is linked to periodontitis.