Acute-phase response signaling, Liver X Receptor-Retinoid X Receptor (LXR/RXR) activation, complement system, Farnesoid X receptor-Retinoid X Receptor (FXR/RXR) activation, coagulation system, intrinsic prothrombin activation pathway, extrinsic prothrombin activation pathway, atherosclerosis signaling, and clathrin-mediated endocytosis signaling were altered in both control and prenatally cocaine-exposed monkeys. Here, F2 is linked to atherosclerosis.