We revealed that, of these shifts that are specific for PBMC, transcriptional activity of HSPA1A/B and HSPA6 was not increased in PMN in PD cases, even considering the fact that in non-stressed conditions PMNs were characterized by higher HSPA1A/B and HSPA6 activity than PBMC (Supplementary Figure S6) [34]. Here, HSPA1A is linked to Parkinson disease.