Other biochemical abnormalities also included hypercalcemia in 10/16 patients, hyperphosphatemia in 10/16 patients, PTH decreased levels in 5/16 patients, deficiency of hepatic metabolite of vitamin D–25-hydroxyvitamin D (25-OHD) in 5/16 patients, hypercalciuria in 7/16 patients, and hyperphosphaturia in 6/16 patients. The gene discussed is PTH; the disease is hypercalcemia disease.