Mean AUROC Hypermutation: (0.81 [SD 0.03] vs. 0.71),MSI (0.86 [0.04] vs. 0.74), CIN (0.83 [0.02] vs. 0.73), BRAF mutation (0.79 [0.01] vs. 0.66), TP53mut (0.73 [0.02] vs. 0.64), KRAS mutation (0.60 [SD 0.04] vs. 0.60), CIMP-high status 0.79 (SD 0.05). This evidence concerns the gene KRAS and cervical squamous intraepithelial neoplasia.