In conclusion, our results demonstrated that a higher PR expression (defined as H-score ≥162.5), tumor grade 1, and lower pretreatment CA125 level (defined as <40 U/mL) could be used to identify patients at low risk of LNM, and our nomogram can aid in decision making regarding lymphadenectomy in patients with endometrioid-type endometrial cancer. Here, PGR is linked to neoplasm.