To analyse the correlation between the expression level of SIPA1 in breast cancer cells and the macrophages that infiltrated the tumour microenvironment, we examined the TMA slide with breast cancer samples for the expression of SIPA1 and that of CD68, a human macrophage-specific marker (Figure 1A, upper panels) with H&E staining (Figure 1A, lower panels). This evidence concerns the gene SIPA1 and breast cancer.