By analysing the transcriptome data of 1100 Breast Invasive Carcinoma (BRCA) samples in The Cancer Genome Atlas Program (TCGA) database, we found that the mRNA expression level of SIPA1 positively correlated with macrophage abundance and pan-macrophage marker CD68 (Figure 1C,D). The gene discussed is CD68; the disease is invasive breast carcinoma.