Thus, we identified essential RBPs for each BC subtype: seven LumA (HSPD1, UBE2M, SART3, USP36, GTPBP4, DHX33, and UPF1), five LumB (RPS21, GNL3L, ZNF207, AQR, and RPL17-C18orf32), seven Her2 (DDX39B, NMT1, ISY1, DARS, HEATR1, MAT2A, and SYF2), and nine Basal (EIF3C, UTP20, TXN, NOP58, ALDOA, CCT2, NOP2, DDX54, and PRMT1) (Figure 6B). Here, TMEM43 is linked to breast cancer.