IL6 and type 1 diabetes mellitus: Also of great interest is the study by Ceriello et al. which showed a significant reduction in FMD response in Type 1 diabetic patients after 2-h hypoglycemia, together with a significant increase in both oxidative (plasma nitrotyrosine and plasma 8-iso-PGF2a) and inflammatory (sICAM-1 and IL-6) markers [34].