A previous investigation proposed calretinin, mesothelin and cytokeratin(CK)5/6 as being the best positive mesothelioma markers for differentiating epithelioid mesotheliomas from RCCs, while the best discriminators for mesothelioma were CD15, MOC-31 and RCC marker antigen (RCCm). Here, MSLN is linked to mesothelioma.