WT1 and Nephroblastoma: The Wilms’ tumor 1 (WT1) gene, mapping to chromosome 11p13, was initially described in 1990 as being a likely predisposing gene for nephroblastoma (Wilms’ tumor) [18,19], a pediatric kidney cancer affecting 1 in 10,000 children [20] and an archetypal model for tumorigenesis resulting from development gone awry [21].