Cordonnier et al. [42], using the same prostate cancer cell line (LNCaP) as Shiota et al. [41] suggested that Hsp27 overexpression, through regulation of the EGF/β-catenin cascade, supported β-catenin’s nuclear translocation and its subsequent binding to the SNAIL 2 (Slug) promoter, eventually promoting EMT [42,49]. The gene discussed is HSPB1; the disease is prostate cancer.