TMPRSS2 and COVID-19: Figure 2J visualized the presence and a significant reduction in the AR level in COVID-19 patients, whereas ECMO-/autopsy specimens and inflamed testicular tissue indicated that IHC staining can be interpreted as specific and reliable. As mentioned, the AR mediates the expression of ACE2 and TMPRSS2, which explains that in most patients with AR deprivation therapy, a reduced risk of getting SARS-CoV-2 infections is notable [43].