CBL and myeloid sarcoma: Nevertheless, it must be emphasized that phlogosis, demyelination, axonal damage, immune reaction, and astrocytic scars (i.e., typical features of MS) have never been observed in human Cbl-deficient central neuropathy (i.e., subacute combined degeneration) or in the Cbl-deficient CNS of different animal species [27,255,352,353].