Inflammation, proliferation, and invasion interplay have been also related to the G-protein-coupled chemoattractant receptor, formylpeptide receptor 1 [96], which is activated by Anx releasing from tumor necrotic cells, determining cell migration, growth, and production of angiogenic factors mediating the SRC-EGFR signaling pathway, leading to ERK/F-actin axis activation and cell chemotaxis. The gene discussed is SRC; the disease is neoplasm.