CXCL8 and Sepsis: Among these selected features, four were disease severity scores (SOFA, SOFA-respiratory, SOFA-coagulation, and ΔSOFA), nine were arterial blood gas parameters (AaDO2, pH, total CO2, ABE, SBC, SBE, HCO3, pCO2, and FiO2), five were sepsis-related novel biomarkers (IL-8, IL-6, angiopoietin-2, E-selectin, and VCAM1), and the rest were routine biochemical and conventional biomarkers (D-dimer, fibrin degradation products, procalcitonin, and lactate).