ITIH4 and primary biliary cholangitis: There was a significant difference between PBC patients and the control group: 148 U/mL vs. 45 U/mL, p < 0.0001 for anti-gp120 antibodies, and 211 U/mL vs. 16 U/mL, p < 0.0001 for anti-p62 antibodies and 176 U/mL vs. 10 U/mL, p < 0.0001 for anti-LBR antibodies.