We observed that as the expression level of lnc-IL7R increased, the probability of COPD decreased with a threshold value of ~0.65 (Chi-squared, X2 = 11.95, p = 0.0005) (Figure 3A), which is reminiscent of a pharmacological effective dose (ED), where the ED is the concentration of lnc-IL7R that elicits a strong anti-COPD biological response. The gene discussed is IL7R; the disease is chronic obstructive pulmonary disease.