In particular, we detected upregulation of certain protein species of APOA1, APOC-II, and APOC-III, which resulted as negatively correlated with peripheral eosinophilia (cell/mm3%) and upregulation of certain protein species of the antioxidants ceruloplasmin and transthyretin. The gene discussed is APOC2; the disease is Increased total eosinophil count.