Furthermore, we evaluated the effect of melatonin on IL-1β and IL-2 expression in the S. aureus infection-associated psoriasis group (Figure 7E and Figure 8E), showing that the treatment with melatonin at the concentrations of 10 nM and 50 nM was able to significantly decrease cytokine positive staining, as shown in the Figure 7F,G and Figure 8F,G (see % total tissue area Figure 7H and Figure 8H, respectively). This evidence concerns the gene IL2 and psoriasis.