MEOX2 and Alzheimer disease: The authors of this report showed that restoring MEOX2 protein expression in endothelial cells from AD patients stimulated angiogenesis, transcriptionally suppressed AFX1 forkhead transcription factor-mediated apoptosis, and increased the levels of low-density lipoprotein receptor 1 (LRP-1), a major Aβ clearance receptor, at the BBB [107].