NPPB and chronic kidney disease: In a recent PEA-based proteomics study in the cohort Mapping of Inflammatory Markers in Chronic Kidney disease (MIMICK), TIM-1, matrix metalloproteinase (MMP)-7, tumor necrosis factor receptor 2 (TNFR2), IL-6, MMP-1, BNP, ST2, hepatocyte growth factor (HGF), TNF-related apoptosis-inducing ligand receptor 2 (TRAIL-R2), spondin-1, and FGF23 showed significant associations with CV death after adjusting for age and sex in 183 HD patients [16].