Moreover, TSPO expression was proven in several brain structures apart from the GL261 tumor such as CA1-CA3 neurons and dentate gyrus in hippocampus, ependyma, cerebellar Purkinje cells, and glial scar of the inoculation process (see Figure 5), which also mirrors PET and autoradiography findings in sham mice (e.g., see Figure 2A). Here, TSPO is linked to neoplasm.