We also expect that the observed reduced granuloma size, along with a decrease in the pro-fibrogenic cytokine TGF-β after L-GSH treatment, could potentially mitigate the extent of restrictive pulmonary fibrotic diseases after an M. tb infection [39,58] in humans; again, further studies using human samples are required to suggest this. This evidence concerns the gene TGFB1 and Granuloma.