SOD1 and amyotrophic lateral sclerosis: Following the notion that a synergy between mitochondrial Ca2+ alterations and ROS production may play a relevant role in ALS [153,184,185], as well as the reported Ca2+-related proteome modifications in SOD1(G93A) cells, we firstly checked the expression of mitochondrial and sarcoplasmic reticulum (SR) Ca2+ transporters in primary SMs from hSOD1(G93A) Tg mice compared to the hSOD1(WT) counterpart as control.