Among the other validated hits were proteins involved in the ubiquitin proteasome system (STAMBP and MYLIP (38)), transcription (MTA1, PKNOX2) (39), translation (EIF4E3) (40), male infertility (RABL2A, DAZAP1) (41), and virus-induced oncogenesis (MTA1) (42, 43). This evidence concerns the gene PKNOX2 and male infertility.