Among the validated BIKE interactors were also proteins involved in host immune responses (ACAA1 (72) and RABL2A (73)), host stress response (FAM120A (74) and DAZAP1 (74)), the ubiquitin proteasome system (STAMBP and MYLIP (38)), transcription (MTA1 (39), PKNOX2 (75)), translation (EIF4E3 (26, 40)), virus-induced oncogenesis (MTA1 (43)), metabolic pathways (ACAA1 (76)), gene regulation (DAZAP1 (41), FAM120A (77)), cell proliferation and differentiation (DAZAP1 (78)), and male infertility (RABL2A, DAZAP1 (41)). Here, MTA1 is linked to male infertility.