MPC1 and neoplasm: Transfer of MPC1 KO OT-I CD8+ T cells in tumor-bearing mice (Figure 4A) did not affect T cell quantity but skewed T cell differentiation from an SLEC to MPEC phenotype in the circulating lymphocyte pool and increased TCM differentiation in the spleen (Figures 4B–4E), which is similar to the Listeria infection model, despite different antigen levels, innate immune cells, and cytokines involved in both models.