CD8A and infection: Naive CD45.2+ CD8+ T cells from OT1 Mpc1fl/fl (referred to as WT) and Mpc1fl/flCd4-Cre (referred to MPC1 KO) mice were transferred into CD45.1.2+ mice, followed by infection with Listeria monocytogenes overexpressing SIINFEKL (Figure 1A).