ACE2 and COVID-19: Perineurial fibroblasts were also ACE2-positive, which is interesting in the light of the neurological manifestations of COVID-19, as the perineurial fibroblasts form a metabolically active permeability barrier and provide structural integrity to the nerve fascicle. In the GI tract, epithelial cells in the tongue, esophagus, duodenum, and ilium were ACE2-positive, which may be of interest in relation to the gastrointestinal manifestations of COVID-19 (Guo et al., 2021) and to SARS-CoV-2 mRNA levels in wastewater (Bertels et al., 2022).