CXCL8 and breast angiosarcoma: In support of this hypothesis, we conducted the ROC curve analysis unveiling that 4 out of 27 systemic cytokines (IL-8, IP-10, MCP-1, and PDGF) yielded an AUC of more than 0.90, thereby establishing their potential as more sensitive and specific biomarkers for differentiating BA patients from healthy controls than others.