In support of this hypothesis, we conducted the ROC curve analysis unveiling that 4 out of 27 systemic cytokines (IL-8, IP-10, MCP-1, and PDGF) yielded an AUC of more than 0.90, thereby establishing their potential as more sensitive and specific biomarkers for differentiating BA patients from healthy controls than others. Here, CCL2 is linked to breast angiosarcoma.