When disease severity was considered, stratified analysis by jaundice status showed that BA patients with jaundice had significantly increased plasma levels of 4 inflammatory cytokines including IL-1β (P = 0.010), IL-6 (P = 0.002), IL-7 (P<0.001), and IL-8 (P<0.001), compared with those without jaundice, as depicted in Fig 2. The gene discussed is IL1B; the disease is Jaundice.