CCL2 and fibrosis: In stratified analysis by fibrosis status, significant elevations in plasma levels of 2 chemokines including eotaxin and IP-10 were found in BA patients with fibrosis, compared with those without fibrosis (P = 0.008, P = 0.008, respectively), while there were no significant differences in plasma levels of MCP-1, MIP-1α, MIP-1β, and RANTES between fibrotic and non-fibrotic groups (Fig 3).